The 22-year-old was involved in a collision with a truck near the club’s training ground and suffered serious head injuries, with the player having to be airlifted from the site of the accident, which took place on the road between Hoffenheim and Heidelberg.
The club also issued a statement, prior to the 0-0 draw with Augsburg on Saturday, confirming the life-threatening injuries that the player suffered.
The news has since shaken the footballing community in Germany, with messages of support coming from across Europe, led by Fifa president Sepp Blatter.
“My thoughts are with him and his family. I hope that he will be well soon,” wrote the head of football’s governing body on Twitter.
“All the best and a speedy recovery, Boris Vukcevic! All the best and get well soon,” tweeted Arsenal striker Lukas Podolski following the game against Chelsea.
“I wish you a speedy recovery Boris Vukcevic! [Keep your] head up, and you can do it,” Borussia Dortmund’s Marco Reus added.
“Dear people, pray and hope that my friend and team-mate of [the Germany] Under-21s, Boris Vukcevic, is healthy again. My thoughts are with him and his family,” said Schalke star Lewis Holtby on his official Facebook page.
His former Hoffenheim team-mate Edson Braafheid also tweeted: “My thoughts are with you. I hope that with God’s help, you get better soon!”
Saturday’s 0-0 draw against Augsburg was played following the request of Vukcevic’s parents, with the 22-year-old still in a critical condition as of Sunday.