The I-4/I-275 interchange (Malfunction Junction) was rebuilt from 2002 to 2006, and I-4 is under staged renovations to be widened from four to six lanes (with eight lanes in certain segments). Much of this work is complete, and all new travel lanes are now open. Eventually, I-4 will be widened again to a total of at least ten lanes (five in each direction). Studies for this project are already underway and construction should commence sometime in the 2010s. Completion of the project should be around 2020.
Eastbound I-4 shifted to its new, permanent alignment between Malfunction Junction and 50th Street on August 8, 2006. The new alignment includes a right-lane ramp exit/entry at the 22nd St/21st St Interchange (The previous left-lane configuration was causing hazardous conditions to commuters since its opening in 2005). On August 11, 2006, a fourth lane opened on eastbound I-4 between the downtown junction and 50th Street (led in by a newly opened third lane on the eastbound I-4 ramp from northbound I-275). And on August 18, the new westbound alignment, just west of 50th Street, opened. The newly opened lanes will improve flow throughout the interchange. The 50th Street overpass however, will not be complete until late 2007. Also, the eastbound I-4 exit ramp to Columbus Drive/50th Street is situated to the left-hand side of the highway (as opposed to its former right-hand side exit). This exit shift went into effect in spring 2006 and is part of the new, permanent interstate configuration.
In Tampa, the exit to 40th Street (SR 569), Exit 2, was closed and demolished in late 2005 due to the ongoing reconstruction of I-4 and to accommodate a proposed connector highway with the Lee Roy Selmon Expressway.
The interchange with what is today I-75 was constructed in the early 1980s.